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Drug Intelligence & Clinical Pharmacy: Vol. 16, No. 5, pp. 409.
© 1982 Harvey Whitney Books Company.
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Research Articles

Convulsions associated with high cumulative doses of metronidazole

TJ Halloran

Metronidazole in high cumulative doses has been associated with convulsions. A case is presented in which this relationship is clear. In all reported cases of metronidazole-associated seizures, the cumulative dose of metronidazole has been high (greater than 40 g). The cumulative dose rather than the serum level is important in the pathogenesis of this complication.


This article has been cited by other articles:


Home page
 Vet PatholHome page
E. J. Olson, S. C. Morales, A. S. McVey, and D. W. Hayden
Putative Metronidazole Neurotoxicosis in a Cat
Vet. Pathol., September 1, 2005; 42(5): 665 - 669.
[Abstract] [Full Text] [PDF]


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Copyright © 1982 by Harvey Whitney Books Company.