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Drug Intelligence & Clinical Pharmacy: Vol. 18, No. 4, pp. 309-310.
© 1984 Harvey Whitney Books Company.
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Research Articles

Hypoglycemia induced by the interaction of chlorpropamide and co-trimoxazole

AM Baciewicz and Swafford WB Jr

Sulfonylureas hypoglycemic action may be potentiated by sulfonamides. This case report describes a 69-year-old female with a hypoglycemic episode suggestive of an interaction between chlorpropamide and sulfamethoxazole (co-trimoxazole). The patient had no renal or liver dysfunction. This interaction is rare but one should be aware of it, especially with combination products.




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Copyright © 1984 by Harvey Whitney Books Company.