 |
 |
 |
 |
 |
 |
 |
|
|
|
|||||||||
|
|||||||||||
Research Articles |
Literature on the effects of beta-blockers on blood glucose is reviewed. Data are presented regarding the adrenergic influences on glucose regulation and the effects of beta-blockade during hypo- and hyperglycemia in normal and diabetic individuals. beta-adrenergic stimulation enhances insulin and glucagon secretion, as well as glycogenolysis, gluconeogenesis, and lipolysis. alpha-adrenergic stimulation inhibits insulin secretion and may inhibit glucagon secretion and enhance liver glycogenolysis. In nondiabetics, beta-blockers represent minimal risk of affecting glucose control. In insulin-dependent diabetics, beta-blockers can prolong, enhance, or alter the symptoms of hypoglycemia, while hyperglycemia appears to be the major risk in noninsulin-dependent diabetics. beta-blockers can potentially increase blood glucose concentrations and antagonize the action of oral hypoglycemic drugs.
This article has been cited by other articles:
|
|
 |
|
  A. C. Cafiero and C. A. Maritz The Impact of Exercise on Age-Related Physiological Changes and Pathological Manifestations Journal of Pharmacy Practice, February 1, 2003; 16(1): 5 - 14. [Abstract] [PDF]
|
|
|
|
 |
|
 J. Chen, T. A. Marciniak, M. J. Radford, Y. Wang, and H. M. Krumholz Beta-blocker therapy for secondary prevention of myocardial infarction in elderly diabetic patients: Results from the national cooperative cardiovascular project J. Am. Coll. Cardiol., November 1, 1999; 34(5): 1388 - 1394. [Abstract] [Full Text] [PDF]
|
|
 |
 |
 |
 |
 |
 |
 |
