The Annals
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Drug Intelligence & Clinical Pharmacy: Vol. 20, No. 10, pp. 786-787.
© 1986 Harvey Whitney Books Company.
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Research Articles

Bradycardia due to trihexyphenidyl hydrochloride

R Blumensohn, G Razoni, A Shalev, and H Munitz

A chronic schizophrenic patient was treated with an anticholinergic drug, trihexyphenidyl hydrochloride. The patient developed, paradoxically, sinus bradycardia. The reaction was specific to trihexyphenidyl and not to other anticholinergic drugs. This antidyskinetic drug is widely used in clinical psychiatric practice and physicians should be aware of this side effect.




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Copyright © 1986 by Harvey Whitney Books Company.