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Drug Intelligence & Clinical Pharmacy: Vol. 20, No. 9, pp. 689-691.
© 1986 Harvey Whitney Books Company.
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Research Articles

Parenteral benzyl alcohol-induced hypersensitivity reaction

JP Wilson, Solimando DA Jr, and MS Edwards

An uncommon hypersensitivity reaction due to parenteral benzyl alcohol administration is reported. One patient treated with benzyl alcohol-preserved cytarabine, vincristine, and heparin solutions developed a systemic hypersensitivity reaction on three separate occasions. Hypersensitivity to benzyl alcohol was confirmed by skin testing. Clinically, the patient presented with a fever and a maculopapular rash on the chest and arms. None of the reactions were life-threatening or required hospitalization of the patient.


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Copyright © 1986 by Harvey Whitney Books Company.