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Drug Intelligence & Clinical Pharmacy: Vol. 21, No. 10, pp. 827-829.
© 1987 Harvey Whitney Books Company.
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Research Articles

Implications of the neglect of stereochemistry in pharmacokinetics and clinical pharmacology

EJ Ariens

An outline is given of the implications of stereoselectivity in biological action and the use of racemic fixed-ratio combinations in pharmacology and pharmacotherapeutics. Pitfalls of the neglect of stereochemistry, such as generation of senseless pharmacokinetic data, are exemplified and emphasized.




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Copyright © 1987 by Harvey Whitney Books Company.