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Drug Intelligence & Clinical Pharmacy: Vol. 22, No. 9, pp. 691-694.
© 1988 Harvey Whitney Books Company.
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Research Articles

Lithium intoxication with acute renal failure and death

SR Rose, W Klein-Schwartz, GM Oderda, RL Gorman, and WW Young

A 65-year-old female presented with only gastrointestinal symptoms eight to ten hours after an acute ingestion of an unknown amount of lithium carbonate. The serum lithium concentration was 8.5 mEq/L. Forty-eight hours postingestion she developed acute renal failure, deteriorating mental status, and cardiovascular collapse. Despite both hemodialysis and peritoneal dialysis the patient died approximately four and one-half days after ingestion. A direct nephrotoxic effect of lithium is proposed.


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Journal of Pharmacy PracticeHome page
J. A. Barone and M. P. Peppers
Therapeutic Drug Monitoring in Emergency Room Toxicology Settings
Journal of Pharmacy Practice, January 1, 1989; 2(6): 347 - 356.
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Copyright © 1988 by Harvey Whitney Books Company.