The Annals
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DICP, The Annals of Pharmacotherapy: Vol. 24, No. 10, pp. 946-947.
© 1990 Harvey Whitney Books Company.
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Research Articles

A case of lisinopril-induced lithium toxicity

CM Baldwin and AZ Safferman

We describe a patient who developed lithium toxicity when lisinopril was substituted for clonidine. Possible mechanisms of angiotensin-converting enzyme (ACE) inhibitor-induced lithium toxicity are discussed. Aggressive serum lithium concentration monitoring and a reduction in the dose of lithium is advised when using ACE inhibitors because of disturbances and shifts in fluid and electrolyte balance.


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Home page
 PsychosomaticsHome page
N. B. Sandson, S. C. Armstrong, and K. L. Cozza
An Overview of Psychotropic Drug-Drug Interactions
Psychosomatics, October 1, 2005; 46(5): 464 - 494.
[Abstract] [Full Text] [PDF]


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Copyright © 1990 by Harvey Whitney Books Company.