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Research Articles |
Cimetidine, a histamine2-receptor antagonist, is used in the treatment and prophylaxis of peptic ulcer disease. Its use is relatively free of serious adverse reactions and only a few accounts of hypersensitivity exist. We report a case of intravenous cimetidine-associated adverse reaction characterized by junctional rhythm, bradycardia, and hypotension apparently not secondary to rapid intravenous cimetidine infusion. The adverse reaction was reproduced upon rechallenge. No previous accounts of this reaction appear clearly defined in the literature nor have such reactions been confirmed by rechallenge.
This article has been cited by other articles:
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  E. J. Drea Transition of Products From Prescription to Over the Counter: The H2 Antagonists Journal of Pharmacy Practice, January 1, 1992; 5(1): 22 - 30. [Abstract] [PDF]
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