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DICP, The Annals of Pharmacotherapy: Vol. 24, No. 6, pp. 583-585.
© 1990 Harvey Whitney Books Company.
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Research Articles

Oxybutynin-induced reflux esophagitis

M Lee and R Sharifi

Oxybutynin has less anticholinergic activity than propantheline bromide. Therefore, oxybutynin is often preferentially prescribed for patients at risk of morbid complications of atropine-like adverse effects. We report a case of oxybutynin-induced reflux esophagitis. This probably resulted from the anticholinergic action of oxybutynin, which decreased lower esophageal sphincter tone. We outline a management approach for patients who experience this adverse effect due to oxybutynin or other commonly prescribed medications.





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Copyright © 1990 by Harvey Whitney Books Company.