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DICP, The Annals of Pharmacotherapy: Vol. 25, No. 3, pp. 249-250.
© 1991 Harvey Whitney Books Company.
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Research Articles

Local tissue reaction to intravenous fluorouracil and leucovorin

GS Umstead, NL Fryer, and DA Decker

Fluorouracil alone can cause a variety of dermatologic adverse effects; however, it is not considered to be a chemical vesicant. We report a case of apparent enhanced local skin reaction from the combination of intravenous fluorouracil and leucovorin. The reaction occurred in the patient's other hand on rechallenge.




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Copyright © 1991 by Harvey Whitney Books Company.