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The Annals of Pharmacotherapy: Vol. 27, No. 9, pp. 1040-1043.
© 1993 Harvey Whitney Books Company.
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Research Articles

Lithium-induced parathyroid dysfunction: a case report and review of the literature

JW Taylor and AJ Bell

OBJECTIVE: Twenty-six cases of lithium-induced hyperparathyroidism have been reported in the literature. This article describes an additional case that illustrates current management recommendations. DESIGN: Case report. Clinical presentation and proposed mechanisms of the suspected drug-induced effect are discussed. CONCLUSIONS: Serum calcium concentrations should be determined before and periodically during long-term lithium carbonate therapy. Discontinuation of therapy in patients who develop lithium-induced parathyroid dysfunction generally corrects calcium and parathyroid hormone concentrations. Surgery is indicated in patients with complications of hyperparathyroidism.


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Copyright © 1993 by Harvey Whitney Books Company.