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The Annals of Pharmacotherapy: Vol. 31, No. 1, pp. 59-60.
© 1997 Harvey Whitney Books Company.
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Research Articles

Sulfadiazine-induced sialadenitis

B Anibarro and JL Fontela

OBJECTIVE: To present a case of sialadenitis induced by sulfadiazine. CASE SUMMARY: A 50-year-old man with bronchitis developed swelling of the parotid glands and floor of the mouth as well as plugging in his ears 2 hours after ingestion of Bronco-aseptilex (sulfadiazine, cyclamate, and guaiacol). Skin-prick tests performed with serial dilutions of sulfadiazine and Bronco-aseptilex were all negative. We then performed oral challenge tests with Bronco-aseptilex, sulfadiazine, and other compounds of the commercial syrup. Enlargement of the salivary glands was observed after oral challenge tests with Bronco-aseptilex and sulfadiazine. CONCLUSIONS: We describe a patient who developed drug-induced sialadenitis. The oral challenge test confirmed that sulfadiazine was the etiologic agent.




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Copyright © 1997 by Harvey Whitney Books Company.