The Annals the journal of Pharmacy Technology
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The Annals of Pharmacotherapy: Vol. 34, No. 4, pp. 479-482. DOI 10.1345/aph.19212
© 2000 Harvey Whitney Books Company.
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Research Articles

Epididymo-orchitis following intravesical bacillus Calmette-Guerin therapy

JJ Menke and Heins JR

OBJECTIVE: To describe a case of epididymo-orchitis that developed four years after treatment with intravesical bacillus Calmette-Guerin (BCG) and to review the incidence of this adverse effect. DATA SOURCES: Information about the patient was obtained from the medical chart. A MEDLINE search of English-language literature (from January 1976 to April 1999) was conducted. STUDY SELECTION: All case reports of BCG-related epididymo-orchitis were evaluated. Review articles describing complications of BCG therapy for bladder cancer and the prevention and treatment of these complications were reviewed. DATA EXTRACTION: Studies were evaluated for reports of BCG-related epididymo-orchitis and its treatment. DATA SYNTHESIS: Our case report is compared with others reported in the literature. The incidence of BCG-associated epididymoorchitis is rare. CONCLUSIONS: Epididymo-orchitis should be considered as a late complication of BCG therapy for bladder cancer. Proper patient selection may help decrease the risk of complications from BCG therapy.


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Copyright © 2000 by Harvey Whitney Books Company.