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Research Articles |
OBJECTIVE: To evaluate the role of secretin in the treatment of children with autism. DATA SOURCE: Literature was assessed through MEDLINE, EMBASE, BIOSIS (November 1998-August 2001), and the World Wide Web. Literature included scientific studies, anecdotal reports, and meeting abstracts. Key search terms included autism and secretin. DATA SYNTHESIS: Autism is a pervasive developmental disorder. Although several treatments exist, no cure has been identified. New information suggests that secretin may be beneficial for this disorder. A critical evaluation of current information about the use of secretin in autism was conducted. CONCLUSIONS: Currently, several anecdotal reports and a few controlled trials with conflicting results have been published regarding the use of secretin in autism. Further studies should be conducted to determine the safety and efficacy of secretin for autism.
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  D. Castermans, V. Wilquet, J. Steyaert, W. van de Ven, J.-P. Fryns, and K. Devriendt Chromosomal Anomalies in Individuals with Autism: A Strategy towards the Identification of Genes Involved in Autism Autism, June 1, 2004; 8(2): 141 - 161. [Abstract] [PDF]
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 S. Hyman Risperidone was safe and effective for short term treatment of children with autism and serious behavioural disturbances Evid. Based Med., January 1, 2003; 8(1): 22 - 22. [Full Text] [PDF]
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