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The Annals of Pharmacotherapy: Vol. 37, No. 11, pp. 1712-1715. DOI 10.1345/aph.1D009
© 2003 Harvey Whitney Books Company.
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DRUG INFORMATION ROUNDS

Safety and Efficacy of Influenza Vaccine in Children

Leslie GB Goldstein, BSPharm

PharmD Student, College of Pharmacy, Idaho State University, Pocatello, ID

Reprints: Leslie GB Goldstein BSPharm, 3466 Park Ave., Oceanside, NY 11572-4339, FAX 516/536-7743, ELSAD{at}aol.com

OBJECTIVE: To describe the safety and efficacy of influenza vaccines in asthmatic children.

DATA SOURCES: Literature was identified by a MEDLINE search (2002–March 2003). Key search terms included asthma, exacerbation, children, vaccine, and influenza.

DATA SYNTHESIS: Concerns that the influenza vaccine may exacerbate asthma attacks have kept many asthmatic children from receiving this immunization. Researchers have conducted studies to determine the burden of influenza on asthmatic children, the safety of influenza vaccines, and their benefit in the presence of glucocorticoid burst therapy in the same population.

CONCLUSIONS: Influenza vaccines tested are safe and efficacious in asthmatic children.

Key Words: asthma, exacerbation, children, influenza, vaccine

Published Online, September 10, 2003. www.theannals.com, DOI 10.1345/aph.1D009


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J. C van der Wouden and H. J Bueving
Comment: safety and efficacy of influenza vaccine in children
Ann. Pharmacother., July 1, 2004; 38(7): 1323 - 1324.
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