The Annals Take our Readership Survey!
home help contact us subscription past issues search current issue
QUICK SEARCH:   [advanced]


     

The Annals of Pharmacotherapy: Vol. 37, No. 12, pp. 1900-1903. DOI 10.1345/aph.1D148
© 2003 Harvey Whitney Books Company.
This Article
Right arrow Résumé Freely available
Right arrow Extracto Freely available
Right arrow Full Text
Right arrow PDF
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Articles Ahead of Print
Right arrow [Order Reprint]
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Sharp, R. P
Right arrow Articles by Gales, B. J
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Sharp, R. P
Right arrow Articles by Gales, B. J

DRUG INFORMATION ROUNDS

Short-Course Oral Antiviral Treatment for Recurrent Genital Herpes

Randall P Sharp, PharmD

Assistant Professor, Department of Pharmacy Practice, School of Pharmacy, Southwestern Oklahoma State University, Weatherford, OK

Barry J Gales, PharmD

Professor, Department of Pharmacy Practice, Southwestern Oklahoma State University

Reprints: Randall P Sharp PharmD, Department of Pharmacy Practice, School of Pharmacy, Southwestern Oklahoma State University, 100 Campus Dr., Weatherford, OK 73096-3098, FAX 405/272-6917, sharpr{at}swosu.edu

OBJECTIVE: To evaluate the literature regarding short-course oral therapy for recurrent genital herpes.

DATA SOURCES: Literature was accessed through MEDLINE (1966–March 2003), IOWA Drug Information Service (1966–March 2003), and International Pharmaceutical Abstracts (1966–March 2003).

DATA SYNTHESIS: Data are available describing short-course (2 or 3 d) therapy with acyclovir and valacyclovir. Short-course acyclovir therapy was superior to placebo. Three- and 5-day regimens of valacyclovir were equivalent. Early initiation of therapy may be more important than duration of therapy.

CONCLUSIONS: More head-to-head studies are needed to determine the most efficacious and cost-effective short-course regimens for recurrent genital herpes.

Key Words: acyclovir, famciclovir, valacyclovir, short-course, genital herpes, recurrent

Published Online, October 10, 2003. www.theannals.com, DOI 10.1345/aph.1D148




homecopy help contact us subscription past issues search current issue
Copyright © 2003 by Harvey Whitney Books Company.