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The Annals of Pharmacotherapy: Vol. 37, No. 2, pp. 282-286. DOI 10.1345/aph.1C225
© 2003 Harvey Whitney Books Company.
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DRUG INFORMATION ROUNDS

Gabapentin for the Treatment of Tremor

Michele A Faulkner, PharmD

Assistant Professor of Pharmacy Practice, School of Pharmacy and Allied Health Professions, Creighton University, Omaha, NE

John M Bertoni, MD PhD

Professor and Chairman, Department of Neurology, School of Medicine, Creighton University

Thomas L Lenz, PharmD

Assistant Professor of Pharmacy Practice, School of Pharmacy and Allied Health Professions, Creighton University

Reprints: Michele A Faulkner PharmD, School of Pharmacy and Allied Health Professions, Creighton University, 2500 California Plaza, Omaha, NE 68178-0401, FAX 402/280-5219, E-mail faulkner{at}creighton.edu

OBJECTIVE: To review the use of the antiepileptic drug gabapentin for the treatment of various types of tremor.

DATA SOURCES: A search of biomedical literature was completed through MEDLINE and EMBASE (1993–May 2002) to identify all clinical trials pertaining to the use of gabapentin for the treatment of tremor in humans.

DATA SYNTHESIS: Outcome data from the few published studies have varied widely. Patient groups have been small, and conclusions have been based largely on subjective patient and investigator ratings.

CONCLUSIONS: A trial of gabapentin is warranted in patients who fail therapy with traditional agents. Improvement should be measured by a patient's perceived functional ability.

Key Words: essential tremor, gabapentin, orthostatic tremor, parkinsonian tremor

Published Online, January 9, 2003. www.theannals.com, DOI


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M. A Pina and P. J Modrego
Dystonia Induced by Gabapentin
Ann. Pharmacother., February 1, 2005; 39(2): 380 - 382.
[Abstract] [Full Text] [PDF]


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