The Annals Take our Readership Survey!
home help contact us subscription past issues search current issue
QUICK SEARCH:   [advanced]


     

The Annals of Pharmacotherapy: Vol. 37, No. 7, pp. 1124-1127. DOI 10.1345/aph.1C415
© 2003 Harvey Whitney Books Company.
This Article
Right arrow Résumé Freely available
Right arrow Extracto Freely available
Right arrow Full Text
Right arrow PDF
Right arrow For Our Patients
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Articles Ahead of Print
Right arrow [Order Reprint]
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Enders, S. J
Right arrow Articles by Enders, J. M
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Enders, S. J
Right arrow Articles by Enders, J. M

DRUG INFORMATION ROUNDS

Isotretinoin and Psychiatric Illness in Adolescents and Young Adults

Shelly J Enders, PharmD

Assistant Professor of Pharmacy Practice, Division of Pharmacy Practice, St. Louis College of Pharmacy, St. Louis, MO

Jason M Enders, PharmD BCPS

Department of Pharmacy, St. Luke's Hospital, Chesterfield, MO; Assistant Professor of Pharmacy Practice, Division of Pharmacy Practice, St. Louis College of Pharmacy

Reprints: Shelly J Enders PharmD, Division of Pharmacy Practice, St. Louis College of Pharmacy, 4588 Parkview Pl., St. Louis, MO 63110-1088, FAX 314/446-8500, E-mail senders{at}stlcop.edu

OBJECTIVE: To evaluate the relationship between isotretinoin and psychiatric illness in adolescents and young adults.

DATA SOURCES: Primary literature located via MEDLINE (1966–December 2002). Key terms were isotretinoin, depression, psychosis, suicide, and adolescents.

DATA SYNTHESIS: Information regarding depression was added to isotretinoin labeling in 1998 following a series of case reports and submitted to the MedWatch system.

CONCLUSIONS: Although a causal relationship may exist between isotretinoin and psychiatric illness in adolescents and young adults, this has not been demonstrated in the literature. Until evidence establishes a presence or lack of causality, prescribers should exercise caution when treating adolescents and young adults with isotretinoin.

Key Words: depression, isotretinoin, psychosis, suicide

Published Online, June 5, 2003. www.theannals.com, DOI 10.1345/aph.1C415




homecopy help contact us subscription past issues search current issue
Copyright © 2003 by Harvey Whitney Books Company.