The Annals Holiday Offer - Save 50%
home help contact us subscription past issues search current issue
QUICK SEARCH:   [advanced]


     


Published Online, 8 June 2004, www.theannals.com, DOI 10.1345/aph.1D512.
 The Annals of Pharmacotherapy: Vol. 38, No. 7, pp. 1293-1296. DOI 10.1345/aph.1D512
© 2004 Harvey Whitney Books Company.
This Article
Right arrow Résumé Freely available
Right arrow Extracto Freely available
Right arrow Full Text
Right arrow PDF
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Articles Ahead of Print
Right arrow [Order Reprint]
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by De Sloover Koch, Y.
Right arrow Articles by Ernst, M. E
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by De Sloover Koch, Y.
Right arrow Articles by Ernst, M. E

DRUG INFORMATION ROUNDS

Selective Serotonin-Reuptake Inhibitors for the Treatment of Hot Flashes

Yvonne De Sloover Koch, PharmD

Ambulatory Care Clinical Pharmacy Specialist, Department of Veterans Affairs Medical Center, Iowa City, IA

Michael E Ernst, PharmD BCPS

Assistant Professor (Clinical), Division of Clinical and Administrative Pharmacy, College of Pharmacy; Department of Family Medicine, College of Medicine, The University of Iowa, Iowa City

Reprints: Michael E Ernst PharmD BCPS, Division of Clinical and Administrative Pharmacy, College of Pharmacy, 01287 PFP, 200 Hawkins Dr., Iowa City, IA 52242-1097, fax 319/384-8515, michael-ernst{at}uiowa.edu

OBJECTIVE: To review the literature evaluating the use of selective serotonin-reuptake inhibitors (SSRIs) for the treatment of hot flashes.

DATA SOURCES: Biomedical literature was accessed through MEDLINE (1966–June 2003), MD Consult, and references of reviewed articles. Key search terms used were hot flashes, vasomotor symptoms, antidepressants, and SSRIs.

DATA SYNTHESIS: Recent evidence from the Women's Health Initiative precludes the use of traditional hormonal therapy in some women. Nonhormonal therapies are possible options, but conflicting evidence of efficacy exists.

CONCLUSIONS: Although further studies are warranted, preliminary data suggest that SSRIs are generally modestly successful in reducing the frequency and severity of hot flashes.

Key Words: antidepressants, hot flashes, selective serotonin-reuptake inhibitors

Published Online, June 8, 2004. www.theannals.com, DOI 10.1345/aph.1D512




homecopy help contact us subscription past issues search current issue
Copyright © 2004 by Harvey Whitney Books Company.