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Published Online, 13 September 2005, www.theannals.com, DOI 10.1345/aph.1G071.
The Annals of Pharmacotherapy: Vol. 39, No. 10, pp. 1640-1646. DOI 10.1345/aph.1G071
© 2005 Harvey Whitney Books Company.
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MEDICATION SAFETY

Disease and Intolerability Documentation in Electronic Patient Records

Henk Buurma, PharmD1, Peter AGM De Smet, PharmD PhD2, Martine Kruijtbosch, MSc3, and Antoine CG Egberts, PharmD PhD4

1 Director, SIR Institute for Pharmacy Practice Research, Leiden, Netherlands; Researcher, Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, Netherlands
2 Researcher, Scientific Institute of Dutch Pharmacists, The Hague, Netherlands; Professor, Department of Clinical Pharmacy, University Medical Centre St Radboud, Nijmegen, Netherlands
3 Researcher, SIR Institute for Pharmacy Practice Research
4 Professor, Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences, Utrecht University; Hospital Pharmacist, Midden-Brabant, TweeSteden Hospital and St. Elisabeth Hospital, Tilburg, Netherlands

Reprints: Dr. Buurma, Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, PO Box 80.082, 3508 TB Utrecht, Netherlands, fax 31 30 2539166, h.buurma{at}stevenshof.nl

BACKGROUND: Documentation of diseases and intolerabilities in electronic patient records (EPRs) in pharmacies is needed to produce an alert in case a contraindicated medicine is prescribed. Limited research is available concerning EPRs in pharmacies.

OBJECTIVE: To study the prevalence and quality of documentation of diseases and intolerabilities in EPRs in a sample of Dutch community pharmacies.

METHODS: Each participating pharmacy (N = 79) collected data on one day in May 2003 for each patient enrolled into the study (N = 687) concerning demographics, drug use, and documentation of diseases and intolerabilities.

RESULTS: In 57.4% of the EPRs, at least one disease and, in 7.9%, at least one intolerability was documented. Higher age, number of drugs used, and chronic disease score were associated with any documentation of a disease/intolerability in the EPR. The highest sensitivity scores (completeness) were found for diabetes (84.7%), asthma/chronic obstructive pulmonary disease (strict definition: 75.9%), and hypothyroidism (75.0%). Rather low values were found for prostatic hyperplasia (55.6%) and heart failure (29.4%). The positive predictive value (reliability) was high for hypothyroidism (100%) and diabetes (87.1%).

CONCLUSIONS: In a selection of Dutch pharmacies, at least one documented disease and/or intolerability was found in the EPR of almost 60% of the patients. Certain diseases were documented to a relatively high degree; others had poorer levels of documentation. For optimal surveillance of drug-disease interactions in pharmacies, the frequency and quality of disease and intolerability documentation need further improvement.

Key Words: electronic patient record, pharmaceutical care, quality

Published Online, September 13, 2005. www.theannals.com, DOI 10.1345/aph.1G071





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