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Published Online, 27 February 2007, www.theannals.com, DOI 10.1345/aph.1H656.
 The Annals of Pharmacotherapy: Vol. 41, No. 3, pp. 502-504. DOI 10.1345/aph.1H656
© 2007 Harvey Whitney Books Company.
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Nesiritide Compared with Milrinone for Cardiac Surgery

Danielle M Blais, PharmD

Cardiothoracic Surgery Specialty Pharmacist, Department of Pharmacy, The Ohio State University Medical Center, 410 W. 10th Ave., 368 Doan Hall, Columbus, OH 43210, fax 614/293-3165, danielle.blais{at}osumc.edu

Reprints: Dr. Blais

Management of patients with low cardiac output syndromes is difficult. Current therapies (ie, inotropes) have associated adverse effects and have not been shown to impact clinical outcomes such as decreased mortality or length of stay. Patients unable to recover from low cardiac output states have end organ damage, increased lengths of stay, increased hospital costs, and readmissions. Nesiritide has been suggested as an alternative or adjunct medication to treat cardiac surgery patients. Recent trials have provided information on the effects of some of these agents on clinical outcomes including respiratory failure, length of stay, and mortality.

Key Words: cardiac surgery, milrinone, nesiritide

Published Online, February 27, 2007. www.theannals.com, DOI 10.1345/aph.1H656

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The Annals 2007 41: 427-432. [Abstract] [Full Text]  





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