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Published Online, 5 February 2009, www.theannals.com, DOI 10.1345/aph.1L464.
The Annals of Pharmacotherapy: Vol. 43, No. 2, pp. 242-250. DOI 10.1345/aph.1L464
© 2009 Harvey Whitney Books Company.
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WOMEN'S HEALTH

Compliance with Osteoporosis Treatment Guidelines in Postmenopausal Women

Cary R Mountjoy, PharmD

Family Medicine Pharmacy Resident, Medical University of South Carolina/South Carolina College of Pharmacy, Charleston, SC

Sarah P Shrader, PharmD BCPS CDE

Assistant Professor, Clinical Pharmacy and Outcome Sciences/Family Medicine, Medical University of South Carolina/South Carolina College of Pharmacy

Kelly R Ragucci, PharmD FCCP BCPS CDE

Associate Professor, Clinical Pharmacy and Outcome Sciences/Family Medicine, Medical University of South Carolina/South Carolina College of Pharmacy

Reprints: Dr. Shrader, Clinical Pharmacy and Outcome Sciences/Family Medicine, South Carolina College of Pharmacy, MUSC Campus, 295 Calhoun St., MSC 192, Charleston, SC 29425, fax 843/792-0436, shrader{at}musc.edu

BACKGROUND: Osteoporosis continues to be poorly managed despite compelling statistics indicating increased morbidity and mortality associated with fractures. Guideline compliance in individual practices must be evaluated to implement improvements in the care of patients with this disease state.

OBJECTIVE: To evaluate compliance with osteoporosis treatment guidelines by physicians and patients at 2 family medicine clinics affiliated with a large university teaching hospital.

METHODS: Postmenopausal women 65 years of age or older with the ICD-9 diagnosis code 733.0 for osteoporosis during the study period between July 2006 and July 2007 were identified through the family medicine electronic medical record (EMR). Of 133 patients, 113 were eligible for inclusion. A retrospective chart review was conducted and prospective voluntary telephone surveys were administered. The EMR of each eligible patient was examined for presence of a baseline dual-energy X-ray absorptiometry (DXA) scan as well as appropriate follow-up DXA monitoring, appropriateness of osteoporosis pharmacotherapy, calcium and vitamin D supplementation, and fracture history. The telephone survey was used to assess the patients' calcium use, nonpharmacologic recommendations received, and fracture incidence after diagnosis of osteoporosis.

RESULTS: Of 113 patients diagnosed with osteoporosis, 68 of 82 (82.9%) had appropriate baseline DXA scans; however, only 9 (13.2%) of these 68 patients had appropriate follow-up scans every 2 years thereafter. Sixty-five (57.5%) patients were on Food and Drug Administration–approved, guideline-endorsed pharmacotherapy for osteoporosis. Thirty-five (70%) of the 50 participants in the telephone survey reported taking calcium regularly, and 41 (82%) patients recalled receiving some nonpharmacologic advice. Thirteen (26%) patients reported a fracture after diagnosis.

CONCLUSIONS: Osteoporosis care can be measurably improved at these clinics with use of baseline and appropriate follow-up DXA scans, increasing the number of patients who receive pharmacotherapy, and providing ongoing reinforcement of nonpharmacologic measures whereby bone health may be maintained.

Key Words: calcium, DXA scan, guidelines, monitoring, osteoporosis, pharmacist intervention, postmenopausal, vitamin D

Published Online, February 3, 2009. www.theannals.com, DOI 10.1345/aph.1L464


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