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Published Online, 15 March 2005, www.theannals.com, DOI 10.1345/aph.1E228.
 The Annals of Pharmacotherapy: Vol. 39, No. 5, pp. 913-917. DOI 10.1345/aph.1E228
© 2005 Harvey Whitney Books Company.
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DRUG INFORMATION ROUNDS

OBJECTIF: Evaluer le rôle du monoxyde d'azote inhalé chez des greffés cardiaques ou pulmonaires.

REVUE DE LITTÉRATURE: Littérature repérée par une recherche sur MEDLINE (1966 à juillet 2004).

RÉSUMÉ: L'hypertension pulmonaire conduisant à l'insuffisance cardiaque droite et les défauts de reperfusion après ischémie sont des complications respectives des transplantations cardiaque et pulmonaire. Cette revue de 7 essais publiés analyse le rôle du monoxyde d'azote chez ces populations et donne des recommandations basées sur la littérature sur le traitement, la posologie, et la surveillance.

CONCLUSIONS: Le monoxyde d'azote présente des effets hémodynamiques bénéfiques dans les suites post-opératoires immédiates chez des greffés cardiaques et des effets hémodynamiques variables chez des greffés pulmonaires. Les données de morbi-mortalité disponibles ne sont pas en faveur de ces indications: il s'agit d'un traitement symptomatique qui nécessite d'autres études.

www.theannals.com, DOI 10.1345/aph.1E228


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This Article
Right arrow Abstract Freely available
Right arrow Extracto Freely available
Right arrow Full Text
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Right arrow Alert me when this article is cited
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Citing Articles
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Google Scholar
Right arrow Articles by Rea, R. S
Right arrow Articles by Seybert, A. L
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PubMed
Right arrow PubMed Citation
Right arrow Articles by Rea, R. S
Right arrow Articles by Seybert, A. L

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Copyright © 2005 by Harvey Whitney Books Company.