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Published Online, 30 May 2006, www.theannals.com, DOI 10.1345/aph.1G404.
 The Annals of Pharmacotherapy: Vol. 40, No. 6, pp. 1125-1133. DOI 10.1345/aph.1G404
© 2006 Harvey Whitney Books Company.
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INFECTIOUS DISEASES

OBJECTIF:Discuter des infections à Staphylococcus aureus résistant à la méthicilline acquis en communauté (SARMAC) et évaluer les opportunités thérapeutiques des anciens antibiotiques.

SOURCE DES DONNÉES:MEDLINE, EMBASE, et la librairie Cochrane (1966-mai 2006) à l'aide des mots-clés: resistance de methicillin, acquise a la communauté, associée a la communauté, traitment, Staphylococcus aureus, mec, et Panton-Valentine leukocidin.

SÉLECTION DES ÉTUDES ET EXTRACTION DES DONNÉES:Tous les articles sont révisés de manière critique et les informations pertinentes sont incluses.

SYNTHESE DES DONNÉES:Il y a une tendance haussière chez les infections à SARMAC. Elles ont pour caractéristiques de ne pas être associées au milieu hospitalier, d'avoir un profil de sensibilité favorable, des génotypes distincts, des temps de génération rapides et des toxines additionnelles. Les options thérapeutiques incluent triméthoprim-sulfaméthoxazole, clindamycine, tétracyclines, fluoroquinolones, et des nouveaux antibiotiques.

CONCLUSIONS:Les infections à SARMAC peuvent être traitées adéquatement avec des anciens antibiotiques per os, comme le triméthoprim-sulfaméthoxazole, la clindamycine, et les tétracyclines. Les fluoroquinolones et le linézolide ne devraient pas être utilisés en première ligne.

www.theannals.com, DOI 10.1345/aph.1G404


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This Article
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Citing Articles
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Google Scholar
Right arrow Articles by Sabol, K. E
Right arrow Articles by Lewis, J. S
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Right arrow Articles by Sabol, K. E
Right arrow Articles by Lewis, J. S, II

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Copyright © 2006 by Harvey Whitney Books Company.