|
|
||||||||||
L'évaluation de la causalité lors d'une interaction médicamenteuse potentielle requiert la prise en considération des propriétés des médicaments impliqués, des facteurs spécifiques au patient, et de la possible contribution des autres médicaments que le patient consomme. L'algorithme de Naranjo a été conçu pour évaluer des effets indésirables aux médicaments seulement, et non des interactions entre médicaments. Plusieurs des questions de l'algorithme de Naranjo ne s'appliquent pas aux interactions entre médicaments alors que d'autres ne spécifient pas le médicament précipitant ou le médicament affecté. Néanmoins, il a été utilisé pour évaluer des interactions entre médicaments. L'échelle de probabilité des interactions médicamenteuses (EPIM) a été développée spécifiquement pour fournir un guide à l'évaluation de causalité des interactions médicamenteuses chez un patient donné. Son utilisation a été prévue pour assister les cliniciens dans l'évaluation des effets indésirables résultant des interactions médicamenteuses potentielles. L'EPIM utilise une série de questions ayant trait à une interaction médicamenteuse potentielle pour estimer un pointage de probabilité. Une évaluation précise par le biais de l'EPIM requiert la connaissance des propriétés pharmacologiques des 2 médicaments impliqués. Une connaissance inadéquate des médicaments impliqués ou encore des mécanismes de base des interactions médicamenteuses sera une limite pour certains utilisateurs. L'EPIM peut aussi servir de guide dans la rédaction des rapports de cas signalant une interaction médicamenteuse et dans l'évaluation des rapports de cas publiés.
www.theannals.com, DOI 10.1345/aph.1H423
This article has been cited by other articles:
![]() |
L. V. Moretti and R. O. Montalvo Elevated International Normalized Ratio associated with concurrent use of sorafenib and warfarin Am. J. Health Syst. Pharm., December 1, 2009; 66(23): 2123 - 2125. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. W. Chock, K. A Packard, and L. K Ohri Comment: Fatal Intracranial Bleed Potentially Due to a Warfarin and Influenza Vaccine Interaction Ann. Pharmacother., November 1, 2009; 43(11): 1913 - 1913. [Full Text] [PDF] |
||||
![]() |
J. A. Morales-Molina, M A. M. Arrebola, P. A. Robles, and J. C. Mangana Possible Interaction Between Topical Terbinafine and Acenocoumarol Ann. Pharmacother., November 1, 2009; 43(11): 1911 - 1912. [Full Text] [PDF] |
||||
![]() |
S. Haroutiunian, Y. Ratz, B. Rabinovich, M. Adam, and A. Hoffman Valproic Acid Plasma Concentration Decreases in a Dose-Independent Manner Following Administration of Meropenem: A Retrospective Study J. Clin. Pharmacol., November 1, 2009; 49(11): 1363 - 1369. [Abstract] [Full Text] [PDF] |
||||
![]() |
W. Yamreudeewong, H. K. Wong, L. M Brausch, and K. R Pulley Probable Interaction Between Warfarin and Marijuana Smoking Ann. Pharmacother., July 1, 2009; 43(7): 1347 - 1353. [Abstract] [Full Text] [PDF] |
||||
![]() |
Y. Y Tsao and J. J Gugger Delirium in a Patient with Toxic Flecainide Plasma Concentrations: The Role of a Pharmacokinetic Drug Interaction with Paroxetine Ann. Pharmacother., July 1, 2009; 43(7): 1366 - 1369. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. Garg and M. Mohammed Decreased INR Response Secondary to Warfarin-Flucloxacillin Interaction Ann. Pharmacother., July 1, 2009; 43(7): 1374 - 1375. [Full Text] [PDF] |
||||
![]() |
G. W. Allison, R. J. Perla, P. P. Belliveau, and S. M. Angelis Elevated creatine phosphokinase levels associated with linezolid therapy Am. J. Health Syst. Pharm., June 15, 2009; 66(12): 1097 - 1100. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. N Carroll and D. G Carroll Fatal Intracranial Bleed Potentially Due to a Warfarin and Influenza Vaccine Interaction Ann. Pharmacother., April 1, 2009; 43(4): 754 - 760. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. Yano, D. Tani, K. Watanabe, H. Tsukamoto, T. Igarashi, T. Nakamura, and M. Masada Evaluation of Potential Interaction Between Vinorelbine and Clarithromycin Ann. Pharmacother., March 1, 2009; 43(3): 453 - 458. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. H Burstein, E. A Boudreau, and W. H Theodore Increase in Tiagabine Serum Concentration with Coadministration of Gemfibrozil Ann. Pharmacother., February 1, 2009; 43(2): 379 - 382. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. L Parker, T. K Hoffmann, M. A. Tucker, and D. J Meier Interaction Between Warfarin and Black Tea Ann. Pharmacother., January 1, 2009; 43(1): 150 - 151. [Full Text] [PDF] |
||||
![]() |
J. Bird and C. Carmona Probable Interaction Between Warfarin and Torsemide Ann. Pharmacother., December 1, 2008; 42(12): 1893 - 1898. [Abstract] [Full Text] [PDF] |
||||
![]() |
C.-M. Wong, Y. Ko, and A. Chan Clinically Significant Drug-Drug Interactions Between Oral Anticancer Agents and Nonanticancer Agents: Profiling and Comparison of Two Drug Compendia Ann. Pharmacother., December 1, 2008; 42(12): 1737 - 1748. [Abstract] [Full Text] [PDF] |
||||
![]() |
K. A. Mergenhagen and O. Sherman Elevated International Normalized Ratio after concurrent ingestion of cranberry sauce and warfarin Am. J. Health Syst. Pharm., November 15, 2008; 65(22): 2113 - 2116. [Abstract] [Full Text] [PDF] |
||||
![]() |
F. Pea, U. Baccarani, M. Tavio, P. Cojutti, G. L. Adani, A. Londero, M. Baraldo, L. Franceschi, M. Furlanut, and P. Viale Pharmacokinetic Interaction Between Everolimus and Antifungal Triazoles in a Liver Transplant Patient Ann. Pharmacother., November 1, 2008; 42(11): 1711 - 1716. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. R Vazquez, M. T Rondina, and R. C Pendleton Azathioprine-Induced Warfarin Resistance Ann. Pharmacother., July 1, 2008; 42(7): 1118 - 1123. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. K Cooper, D. G Brock, and C. M McDaniel Interaction Between Levodopa and Enteral Nutrition Ann. Pharmacother., March 1, 2008; 42(3): 439 - 442. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. Moellentin, C. Picone, and E. Leadbetter Memantine-Induced Myoclonus and Delirium Exacerbated by Trimethoprim Ann. Pharmacother., March 1, 2008; 42(3): 443 - 447. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. G. Scordo, H. Melhus, E. Stjernberg, A. M. Edvardsson, and M. Wadelius Warfarin-Noscapine Interaction: A Series of Four Case Reports Ann. Pharmacother., March 1, 2008; 42(3): 448 - 450. [Full Text] [PDF] |
||||
![]() |
H. CACI and F. BAYLE A Case of Disulfiram-Methylphenidate Interaction: Implications for Treatment Am J Psychiatry, November 1, 2007; 164(11): 1759 - 1759. [Full Text] [PDF] |
||||
![]() |
I. Spriet, J. Goyens, W. Meersseman, A. Wilmer, L. Willems, and W. V. Paesschen Interaction Between Valproate and Meropenem: A Retrospective Study Ann. Pharmacother., July 1, 2007; 41(7): 1130 - 1136. [Abstract] [Full Text] [PDF] |
||||
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||