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The Annals of Pharmacotherapy: Vol. 37, No. 3, pp. 442-446. DOI 10.1345/aph.1C277
© 2003 Harvey Whitney Books Company.
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DRUG INFORMATION ROUNDS

OBJETIVO: Evaluar el efecto de los inhibidores selectivo de cyclooxygenase-2 (ISC) en la presión sanguínea.

EXTRACCIÓN DE DATOS: Se accesó literatura clínica usando las palabras claves: inhibidores selectivo COX-2, agente anti-inflamatorio no esteroidal, celecoxib, estudios prospectivos rofecoxib, e hipertensión.

SÍNTESIS DE DATOS: Los datos de estudios prospectivos sobre los efectos de ISC en la presión sanguínea son conflictivos. Algunos estudios han reportado un aumento en presión sanguínea como efecto adverso de los ISC.

CONCLUSIONES: Estudios adicionales que evaluen los efectos de los ISC en la presión sanguínea son necesarios. Estos medicamentos deberían ser usados con precaución en pacientes hipertensos y si fuera necesario utilizarlo; se debe proveer un seguimiento contínuo de la presión sanguínea.




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J. Wang, C D. Mullins, M. Mamdani, D. A Rublee, and F. T Shaya
New Diagnosis of Hypertension Among Celecoxib and Nonselective NSAID Users: A Population-Based Cohort Study
Ann. Pharmacother., June 1, 2007; 41(6): 937 - 943.
[Abstract] [Full Text] [PDF]

This Article
Right arrow Abstract Freely available
Right arrow Résumé Freely available
Right arrow Full Text
Right arrow PDF
Right arrow For Our Patients
Right arrow Alert me when this article is cited
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Citing Articles
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Right arrow Articles by Johnson, D. L
Right arrow Articles by Phillips, B. B.
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PubMed
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Right arrow Articles by Johnson, D. L
Right arrow Articles by Phillips, B. B.

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Copyright © 2003 by Harvey Whitney Books Company.