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The Annals of Pharmacotherapy: Vol. 37, No. 9, pp. 1321-1324. DOI 10.1345/aph.1D050
© 2003 Harvey Whitney Books Company.
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DRUG INFORMATION ROUNDS

OBJETIVO: Evaluar la eficacia y la seguridad de la olanzapina en el tratamiento de los transtornos psicoticos y comportamentales de la enfermedad de Alzheimer.

FUENTES DE INFORMACIÓN: Se han realizado bùsquedas en MEDLINE (desde 1996 hasta enero 2003) y en Science Citation Index. Los términos buscados ha sido olanzapina, Alzheimer(s), y demencia.

SÍNTESIS: Se han revisado 4 estudios con olanzapina de los cuales se han realizado analisis post-hoc.

CONCLUSIONES: La olanzapina parece eficaz en el tratamiento de los transtornos psicoticos y de comportamineto asociados a la enfermedad de Alzheimer. Sin embargo, no se ha determinado aún la dosis adecuada. El beneficio de la terapia con olanzapina debería evaluarse considerando los posibles efectos adversos y los tratamientos alternativos.





This Article
Right arrow Abstract Freely available
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Right arrow Articles by Schatz, R. A
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Copyright © 2003 by Harvey Whitney Books Company.