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The Annals of Pharmacotherapy: Vol. 38, No. 1, pp. 54-57. DOI 10.1345/aph.1C477
© 2004 Harvey Whitney Books Company.
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OBJETIVO: Comunicar un caso de erupción psoriasiforme inducida por infliximab.

RESUMEN DEL CASO: Una mujer de 46 años con fístula enterocutánea secundaria a enfermedad de Crohn desarrolló placas eritematosas, descamativas y pruriginosas en los codos, las rodillas, las manos y los glúteos tras recibir la segunda y tercera dosis de un tratamiento con infliximab intravenoso. El estudio histopatológico mostró un patrón liquenoide. No aparecieron nuevas lesiones tras suspender el tratamiento con infliximab.

DISCUSIÓN: Se han descrito diversos tipos de reacciones cutáneas secundarias al infliximab, un anticuerpo monoclonal anti-TNF-alfa. No se ha descrito con anterioridad una dermatitis psoriasiforme como reacción cutánea por infliximab, pero existen múltiples comunicaciones sobre dermatitis psoriasiformes secundarias a otros fármacos. Una evaluación objetiva de la causalidad determinó este efecto adverso como probable.

CONCLUSIONES: Se describe un caso manifestado clínicamente como una erupción psoriasiforme y que mostraba una imagen histopatológica de dermatitis liquenoide. Este patrón clínico-patológico disociado de reacción cutánea no ha sido referido con anterioridad como un efecto secundario del tratamiento con infliximab.




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This Article
Right arrow Abstract Freely available
Right arrow Résumé Freely available
Right arrow Full Text
Right arrow PDF
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Articles Ahead of Print
Right arrow [Order Reprint]
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Verea, M. M
Right arrow Articles by Fonseca, E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Verea, M. M
Right arrow Articles by Fonseca, E.

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Copyright © 2004 by Harvey Whitney Books Company.