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Published Online, 19 December 2006, www.theannals.com, DOI 10.1345/aph.1H456.
 The Annals of Pharmacotherapy: Vol. 41, No. 1, pp. 129-132. DOI 10.1345/aph.1H456
© 2007 Harvey Whitney Books Company.
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Los antagonistas de la aldosterona constituyen el pilar principal de la terapia en pacientes con hipertensión causado por el aldosteronismo primario. Sin embargo, según nuestra experiencia, estos pacientes reciben tratamiento con inhibidores de la ECA de acuerdo con las guías prácticas que se aplican a la población general con hipertensión. Sin embargo, creemos que esta práctica resulta inapropiada debido a que los inhibidores de la ECA no pueden reducir la presión arterial en aquellos pacientes con niveles bajos de renina. Además, es poco probable que los efectos pleitrópicos de los inhibidores de la ECA proporcionen un beneficio significativo cuando no reducen la presión arterial. Por ello, debería desaconsejarse la utilización de los inhibidores de la ECA para la mayoría de los pacientes con aldosteronismo primario, incluso con enfermedad renal o cardiaca.

Enrique Muñoz Soler

www.theannals.com, DOI 10.1345/aph.1H456



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Copyright © 2007 by Harvey Whitney Books Company.